2023
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6. | Piccinini, A M; Krauß, S Editorial: In celebration of women in science: RNA networks and biology Journal Article Front Mol Biosci, 10 , pp. 1162378, 2023, ISSN: 2296-889X (Print) 2296-889x. Links | BibTeX | Tags: Krauss, RNA @article{RN13764,
title = {Editorial: In celebration of women in science: RNA networks and biology},
author = {A M Piccinini and S Krauß},
doi = {10.3389/fmolb.2023.1162378},
issn = {2296-889X (Print) 2296-889x},
year = {2023},
date = {2023-01-01},
journal = {Front Mol Biosci},
volume = {10},
pages = {1162378},
keywords = {Krauss, RNA},
pubstate = {published},
tppubtype = {article}
}
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2021
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5. | A, Heinz; DK, Nabariya; S., Krauss Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity Journal Article Toxins (Basel), 2021. Links | BibTeX | Tags: Krauss @article{Krauss2021b,
title = {Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity},
author = {Heinz A and Nabariya DK and Krauss S.},
doi = {https://doi.org/10.3390/toxins13070487},
year = {2021},
date = {2021-07-14},
journal = {Toxins (Basel)},
keywords = {Krauss},
pubstate = {published},
tppubtype = {article}
}
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4. | A., Heinz; D.K., Nabariya; S, Krauß Huntington’s Disease and Neurodegeneration Journal Article Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham. , 2021. Links | BibTeX | Tags: Krauss @article{Krauss2021b,
title = {Huntington’s Disease and Neurodegeneration},
author = {Heinz A. and Nabariya D.K. and Krauß S},
doi = {https://doi.org/10.1007/978-3-030-71519-9_226-1},
year = {2021},
date = {2021-06-25},
journal = {Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham. },
keywords = {Krauss},
pubstate = {published},
tppubtype = {article}
}
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3. | DV, Berdnikova; P, Carloni; S, Krauß; G., Rossetti Role and Perspective of Molecular Simulation-Based Investigation of RNA-Ligand Interaction: From Small Molecules and Peptides to Photoswitchable RNA Binding Journal Article Molecules, 2021. Abstract | Links | BibTeX | Tags: Krauss @article{Krauss2021b,
title = {Role and Perspective of Molecular Simulation-Based Investigation of RNA-Ligand Interaction: From Small Molecules and Peptides to Photoswitchable RNA Binding},
author = {Berdnikova DV and Carloni P and Krauß S and Rossetti G.},
doi = {https://doi.org/10.3390/molecules26113384},
year = {2021},
date = {2021-06-03},
journal = {Molecules},
abstract = {Abstract
Aberrant RNA–protein complexes are formed in a variety of diseases. Identifying the ligands that interfere with their formation is a valuable therapeutic strategy. Molecular simulation, validated against experimental data, has recently emerged as a powerful tool to predict both the pose and energetics of such ligands. Thus, the use of molecular simulation may provide insight into aberrant molecular interactions in diseases and, from a drug design perspective, may allow for the employment of less wet lab resources than traditional in vitro compound screening approaches. With regard to basic research questions, molecular simulation can support the understanding of the exact molecular interaction and binding mode. Here, we focus on examples targeting RNA–protein complexes in neurodegenerative diseases and viral infections. These examples illustrate that the strategy is rather general and could be applied to different pharmacologically relevant approaches. We close this study by outlining one of these approaches, namely the light-controllable association of small molecules with RNA, as an emerging approach in RNA-targeting therapy. },
keywords = {Krauss},
pubstate = {published},
tppubtype = {article}
}
Abstract
Aberrant RNA–protein complexes are formed in a variety of diseases. Identifying the ligands that interfere with their formation is a valuable therapeutic strategy. Molecular simulation, validated against experimental data, has recently emerged as a powerful tool to predict both the pose and energetics of such ligands. Thus, the use of molecular simulation may provide insight into aberrant molecular interactions in diseases and, from a drug design perspective, may allow for the employment of less wet lab resources than traditional in vitro compound screening approaches. With regard to basic research questions, molecular simulation can support the understanding of the exact molecular interaction and binding mode. Here, we focus on examples targeting RNA–protein complexes in neurodegenerative diseases and viral infections. These examples illustrate that the strategy is rather general and could be applied to different pharmacologically relevant approaches. We close this study by outlining one of these approaches, namely the light-controllable association of small molecules with RNA, as an emerging approach in RNA-targeting therapy. |
2020
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2. | Collison, A M; Sokulsky, L A; Nightingale, S; Percival, E; LeFevre, A; Meredith, J; Krauss, S; Mattes, Fosterand P S J In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis Journal Article 2020. Links | BibTeX | Tags: Krauss, Neurobiologie @article{Mattes2020,
title = {In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis},
author = {A M Collison and L A Sokulsky and S Nightingale and E Percival and A LeFevre and J Meredith and S Krauss and P S Fosterand J Mattes},
editor = {Clinical & Translational Immunology },
url = {https://doi.org/10.1002/cti2.1210},
doi = {10.1002/cti2.1210},
year = {2020},
date = {2020-11-23},
keywords = {Krauss, Neurobiologie},
pubstate = {published},
tppubtype = {article}
}
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1. | Lountzi, D; Henzel, K; Jazbec, K; Banow, D; Krauss, S; Rozman, P; Ehinger, D Effects of heterochronic, non-myeloablative bone marrow transplantation on age-releated behavioural changes in mice Journal Article 2020. Links | BibTeX | Tags: Krauss, Neurobiologie @article{Lountzi2020,
title = {Effects of heterochronic, non-myeloablative bone marrow transplantation on age-releated behavioural changes in mice},
author = { D Lountzi and K Henzel and K Jazbec and D Banow and S Krauss and P Rozman and D Ehinger },
editor = {Mechanisms of Ageing and Develpoment },
url = {https://doi.org/10.1016/j.mad.2020.111327},
doi = {10.1016/j.mad.2020.111327},
year = {2020},
date = {2020-10-01},
keywords = {Krauss, Neurobiologie},
pubstate = {published},
tppubtype = {article}
}
|