2023
|
| 39. | Piccinini, A M; Krauß, S Editorial: In celebration of women in science: RNA networks and biology Artikel Front Mol Biosci, 10 , S. 1162378, 2023, ISSN: 2296-889X (Print) 2296-889x. Links | BibTeX @article{RN13764,
title = {Editorial: In celebration of women in science: RNA networks and biology},
author = {A M Piccinini and S Krauß},
doi = {10.3389/fmolb.2023.1162378},
issn = {2296-889X (Print) 2296-889x},
year = {2023},
date = {2023-01-01},
journal = {Front Mol Biosci},
volume = {10},
pages = {1162378},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2022
|
| 38. | Nabariya, D K; Heinz, A; Derksen, S; Krauß, S Intracellular and intercellular transport of RNA organelles in CXG repeat disorders: The strength of weak ties Artikel Front Mol Biosci, 9 , S. 1000932, 2022, ISSN: 2296-889X (Print) 2296-889x. Links | BibTeX @article{RN13762,
title = {Intracellular and intercellular transport of RNA organelles in CXG repeat disorders: The strength of weak ties},
author = {D K Nabariya and A Heinz and S Derksen and S Krauß},
doi = {10.3389/fmolb.2022.1000932},
issn = {2296-889X (Print) 2296-889x},
year = {2022},
date = {2022-01-01},
journal = {Front Mol Biosci},
volume = {9},
pages = {1000932},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2021
|
| 37. | A, Heinz; DK, Nabariya; S., Krauss Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity Artikel Toxins (Basel), 2021. Links | BibTeX @article{Krauss2021b,
title = {Huntingtin and Its Role in Mechanisms of RNA-Mediated Toxicity},
author = {Heinz A and Nabariya DK and Krauss S.},
doi = {https://doi.org/10.3390/toxins13070487},
year = {2021},
date = {2021-07-14},
journal = {Toxins (Basel)},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 36. | A., Heinz; D.K., Nabariya; S, Krauß Huntington’s Disease and Neurodegeneration Artikel Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham. , 2021. Links | BibTeX @article{Krauss2021b,
title = {Huntington’s Disease and Neurodegeneration},
author = {Heinz A. and Nabariya D.K. and Krauß S},
doi = {https://doi.org/10.1007/978-3-030-71519-9_226-1},
year = {2021},
date = {2021-06-25},
journal = {Kostrzewa R.M. (eds) Handbook of Neurotoxicity. Springer, Cham. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 35. | DV, Berdnikova; P, Carloni; S, Krauß; G., Rossetti Role and Perspective of Molecular Simulation-Based Investigation of RNA-Ligand Interaction: From Small Molecules and Peptides to Photoswitchable RNA Binding Artikel Molecules, 2021. Abstract | Links | BibTeX @article{Krauss2021b,
title = {Role and Perspective of Molecular Simulation-Based Investigation of RNA-Ligand Interaction: From Small Molecules and Peptides to Photoswitchable RNA Binding},
author = {Berdnikova DV and Carloni P and Krauß S and Rossetti G.},
doi = {https://doi.org/10.3390/molecules26113384},
year = {2021},
date = {2021-06-03},
journal = {Molecules},
abstract = {Abstract
Aberrant RNA–protein complexes are formed in a variety of diseases. Identifying the ligands that interfere with their formation is a valuable therapeutic strategy. Molecular simulation, validated against experimental data, has recently emerged as a powerful tool to predict both the pose and energetics of such ligands. Thus, the use of molecular simulation may provide insight into aberrant molecular interactions in diseases and, from a drug design perspective, may allow for the employment of less wet lab resources than traditional in vitro compound screening approaches. With regard to basic research questions, molecular simulation can support the understanding of the exact molecular interaction and binding mode. Here, we focus on examples targeting RNA–protein complexes in neurodegenerative diseases and viral infections. These examples illustrate that the strategy is rather general and could be applied to different pharmacologically relevant approaches. We close this study by outlining one of these approaches, namely the light-controllable association of small molecules with RNA, as an emerging approach in RNA-targeting therapy. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Abstract
Aberrant RNA–protein complexes are formed in a variety of diseases. Identifying the ligands that interfere with their formation is a valuable therapeutic strategy. Molecular simulation, validated against experimental data, has recently emerged as a powerful tool to predict both the pose and energetics of such ligands. Thus, the use of molecular simulation may provide insight into aberrant molecular interactions in diseases and, from a drug design perspective, may allow for the employment of less wet lab resources than traditional in vitro compound screening approaches. With regard to basic research questions, molecular simulation can support the understanding of the exact molecular interaction and binding mode. Here, we focus on examples targeting RNA–protein complexes in neurodegenerative diseases and viral infections. These examples illustrate that the strategy is rather general and could be applied to different pharmacologically relevant approaches. We close this study by outlining one of these approaches, namely the light-controllable association of small molecules with RNA, as an emerging approach in RNA-targeting therapy. |
| 34. | Furtado, Gabriel Vasata; Yang, Jing; Wu, Di; Papagiannopoulos, Christos I; Terpstra, Hanna M; Kuiper, Elsiena E F; Krauss, Sybille; Zhu, Wei-Guo; Kampinga, Harm H; Bergink, Steven FOXO1 controls protein synthesis and transcript abundance of mutant polyglutamine proteins, preventing protein aggregation. Artikel Human Molecular Genetics, 2021, ( ). Abstract | Links | BibTeX @article{Krauss2021,
title = {FOXO1 controls protein synthesis and transcript abundance of mutant polyglutamine proteins, preventing protein aggregation.},
author = {Gabriel Vasata Furtado and Jing Yang and Di Wu and Christos I Papagiannopoulos and Hanna M Terpstra and E F Elsiena Kuiper and Sybille Krauss and Wei-Guo Zhu and Harm H Kampinga and Steven Bergink},
editor = { },
doi = {10.1093},
year = {2021},
date = {2021-06-01},
journal = {Human Molecular Genetics},
abstract = { Abstract
FOXO1, a transcription factor downstream of the insulin/insulin like growth factor axis, has been linked to protein degradation. Elevated expression of FOXO orthologs can also prevent the aggregation of cytosine adenine guanine (CAG)-repeat disease causing polyglutamine (polyQ) proteins but whether FOXO1 targets mutant proteins for degradation is unclear. Here, we show that increased expression of FOXO1 prevents toxic polyQ aggregation in human cells while reducing FOXO1 levels has the opposite effect and accelerates it. Although FOXO1 indeed stimulates autophagy, its effect on polyQ aggregation is independent of autophagy, ubiquitin–proteasome system (UPS) mediated protein degradation and is not due to a change in mutant polyQ protein turnover. Instead, FOXO1 specifically downregulates protein synthesis rates from expanded pathogenic CAG repeat transcripts. FOXO1 orchestrates a change in the composition of proteins that occupy mutant expanded CAG transcripts, including the recruitment of IGF2BP3. This mRNA binding protein enables a FOXO1 driven decrease in pathogenic expanded CAG transcript- and protein levels, thereby reducing the initiation of amyloidogenesis. Our data thus demonstrate that FOXO1 not only preserves protein homeostasis at multiple levels, but also reduces the accumulation of aberrant RNA species that may co-contribute to the toxicity in CAG-repeat diseases.},
note = { },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Abstract
FOXO1, a transcription factor downstream of the insulin/insulin like growth factor axis, has been linked to protein degradation. Elevated expression of FOXO orthologs can also prevent the aggregation of cytosine adenine guanine (CAG)-repeat disease causing polyglutamine (polyQ) proteins but whether FOXO1 targets mutant proteins for degradation is unclear. Here, we show that increased expression of FOXO1 prevents toxic polyQ aggregation in human cells while reducing FOXO1 levels has the opposite effect and accelerates it. Although FOXO1 indeed stimulates autophagy, its effect on polyQ aggregation is independent of autophagy, ubiquitin–proteasome system (UPS) mediated protein degradation and is not due to a change in mutant polyQ protein turnover. Instead, FOXO1 specifically downregulates protein synthesis rates from expanded pathogenic CAG repeat transcripts. FOXO1 orchestrates a change in the composition of proteins that occupy mutant expanded CAG transcripts, including the recruitment of IGF2BP3. This mRNA binding protein enables a FOXO1 driven decrease in pathogenic expanded CAG transcript- and protein levels, thereby reducing the initiation of amyloidogenesis. Our data thus demonstrate that FOXO1 not only preserves protein homeostasis at multiple levels, but also reduces the accumulation of aberrant RNA species that may co-contribute to the toxicity in CAG-repeat diseases. |
2020
|
| 33. | Collison, A M; Sokulsky, L A; Nightingale, S; Percival, E; LeFevre, A; Meredith, J; Krauss, S; Mattes, Fosterand P S J In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis Artikel 2020. Links | BibTeX @article{Mattes2020,
title = {In vivo targeting of miR‐223 in experimental eosinophilic oesophagitis},
author = {A M Collison and L A Sokulsky and S Nightingale and E Percival and A LeFevre and J Meredith and S Krauss and P S Fosterand J Mattes},
editor = {Clinical & Translational Immunology },
url = {https://doi.org/10.1002/cti2.1210},
doi = {10.1002/cti2.1210},
year = {2020},
date = {2020-11-23},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 32. | Lountzi, D; Henzel, K; Jazbec, K; Banow, D; Krauss, S; Rozman, P; Ehinger, D Effects of heterochronic, non-myeloablative bone marrow transplantation on age-releated behavioural changes in mice Artikel 2020. Links | BibTeX @article{Lountzi2020,
title = {Effects of heterochronic, non-myeloablative bone marrow transplantation on age-releated behavioural changes in mice},
author = { D Lountzi and K Henzel and K Jazbec and D Banow and S Krauss and P Rozman and D Ehinger },
editor = {Mechanisms of Ageing and Develpoment },
url = {https://doi.org/10.1016/j.mad.2020.111327},
doi = {10.1016/j.mad.2020.111327},
year = {2020},
date = {2020-10-01},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2019
|
| 31. | Krauss, S; Evert, B O The Role of MicroRNAs in Spinocerebellar Ataxia Type 3 Artikel J Mol Biol, 431 (9), S. 1729-1742, 2019, ISSN: 1089-8638 (Electronic)
0022-2836 (Linking). Links | BibTeX @article{RN33b,
title = {The Role of MicroRNAs in Spinocerebellar Ataxia Type 3},
author = {S Krauss and B O Evert},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30664869},
doi = {10.1016/j.jmb.2019.01.019},
issn = {1089-8638 (Electronic)
0022-2836 (Linking)},
year = {2019},
date = {2019-01-01},
journal = {J Mol Biol},
volume = {431},
number = {9},
pages = {1729-1742},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 30. | Reichenbach, N; Delekate, A; Plescher, M; Schmitt, F; Krauss, S; Blank, N; Halle, A; Petzold, G C Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model Artikel EMBO Mol Med, 11 (2), 2019, ISSN: 1757-4684 (Electronic)
1757-4676 (Linking). Links | BibTeX @article{RN30b,
title = {Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model},
author = {N Reichenbach and A Delekate and M Plescher and F Schmitt and S Krauss and N Blank and A Halle and G C Petzold},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30617153},
doi = {10.15252/emmm.201809665},
issn = {1757-4684 (Electronic)
1757-4676 (Linking)},
year = {2019},
date = {2019-01-01},
journal = {EMBO Mol Med},
volume = {11},
number = {2},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 29. | Schilling, J; Broemer, M; Atanassov, I; Duernberger, Y; Vorberg, I; Dieterich, C; Dagane, A; Dittmar, G; Wanker, E; van Roon-Mom, W; Winter, J; Krauss, S Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease Artikel J Mol Biol, 2019, ISSN: 1089-8638 (Electronic)
0022-2836 (Linking). Links | BibTeX @article{RN16b,
title = {Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease},
author = {J Schilling and M Broemer and I Atanassov and Y Duernberger and I Vorberg and C Dieterich and A Dagane and G Dittmar and E Wanker and W van Roon-Mom and J Winter and S Krauss},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30711541},
doi = {10.1016/j.jmb.2019.01.034},
issn = {1089-8638 (Electronic)
0022-2836 (Linking)},
year = {2019},
date = {2019-01-01},
journal = {J Mol Biol},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2018
|
| 28. | Arnoux, I; Willam, M; Griesche, N; Krummeich, J; Watari, H; Offermann, N; Weber, S; Dey, Narayan P; Chen, C; Monteiro, O; Buettner, S; Meyer, K; Bano, D; Radyushkin, K; Langston, R; Lambert, J J; Wanker, E; Methner, A; Krauss, S; Schweiger, S; Stroh, A Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease Artikel Elife, 7 , 2018, ISSN: 2050-084X (Electronic)
2050-084X (Linking). Links | BibTeX @article{RN2l,
title = {Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease},
author = {I Arnoux and M Willam and N Griesche and J Krummeich and H Watari and N Offermann and S Weber and P Narayan Dey and C Chen and O Monteiro and S Buettner and K Meyer and D Bano and K Radyushkin and R Langston and J J Lambert and E Wanker and A Methner and S Krauss and S Schweiger and A Stroh},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30179155},
doi = {10.7554/eLife.38744},
issn = {2050-084X (Electronic)
2050-084X (Linking)},
year = {2018},
date = {2018-01-01},
journal = {Elife},
volume = {7},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 27. | Evert, B O; Nalavade, R; Jungverdorben, J; Matthes, F; Weber, S; Rajput, A; Bonn, S; Brustle, O; Peitz, M; Krauss, S Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3 Artikel PLoS One, 13 (8), S. e0201794, 2018, ISSN: 1932-6203 (Electronic)
1932-6203 (Linking). Links | BibTeX @article{RN3l,
title = {Upregulation of miR-370 and miR-543 is associated with reduced expression of heat shock protein 40 in spinocerebellar ataxia type 3},
author = {B O Evert and R Nalavade and J Jungverdorben and F Matthes and S Weber and A Rajput and S Bonn and O Brustle and M Peitz and S Krauss},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30086154},
doi = {10.1371/journal.pone.0201794},
issn = {1932-6203 (Electronic)
1932-6203 (Linking)},
year = {2018},
date = {2018-01-01},
journal = {PLoS One},
volume = {13},
number = {8},
pages = {e0201794},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 26. | Krauss, S; Nalavade, R; Weber, S; Carter, K; Evert, B O Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients Artikel Microrna, 2018, ISSN: 2211-5374 (Electronic). Links | BibTeX @article{RN9b,
title = {Upregulation of miR-25 and miR-181 Family Members Correlates with Reduced Expression of ATXN3 in Lymphocytes from SCA3 Patients},
author = {S Krauss and R Nalavade and S Weber and K Carter and B O Evert},
url = {https://www.ncbi.nlm.nih.gov/pubmed/30147021},
doi = {10.2174/2211536607666180821162403},
issn = {2211-5374 (Electronic)},
year = {2018},
date = {2018-01-01},
journal = {Microrna},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 25. | Matthes, F; Hettich, M M; Schilling, J; Flores-Dominguez, D; Blank, N; Wiglenda, T; Buntru, A; Wolf, H; Weber, S; Vorberg, I; Dagane, A; Dittmar, G; Wanker, E; Ehninger, D; Krauss, S Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis Artikel Cell Death Discovery, 4 (4), 2018. Links | BibTeX @article{RN12b,
title = {Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis},
author = {F Matthes and M M Hettich and J Schilling and D Flores-Dominguez and N Blank and T Wiglenda and A Buntru and H Wolf and S Weber and I Vorberg and A Dagane and G Dittmar and E Wanker and D Ehninger and S Krauss},
doi = {DOI 10.1038/s41420-017-0003-8},
year = {2018},
date = {2018-01-01},
journal = {Cell Death Discovery},
volume = {4},
number = {4},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 24. | Matthes, F; Massari, S; Bochicchio, A; Schorpp, K; Schilling, J; Weber, S; Offermann, N; Desantis, J; Wanker, E; Carloni, P; Hadian, K; Tabarrini, O; Rossetti, G; Krauss, S Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder Artikel ACS Chem Neurosci, 9 (6), S. 1399-1408, 2018, ISSN: 1948-7193 (Electronic)
1948-7193 (Linking). Links | BibTeX @article{RN29b,
title = {Reducing Mutant Huntingtin Protein Expression in Living Cells by a Newly Identified RNA CAG Binder},
author = {F Matthes and S Massari and A Bochicchio and K Schorpp and J Schilling and S Weber and N Offermann and J Desantis and E Wanker and P Carloni and K Hadian and O Tabarrini and G Rossetti and S Krauss},
url = {https://www.ncbi.nlm.nih.gov/pubmed/29506378},
doi = {10.1021/acschemneuro.8b00027},
issn = {1948-7193 (Electronic)
1948-7193 (Linking)},
year = {2018},
date = {2018-01-01},
journal = {ACS Chem Neurosci},
volume = {9},
number = {6},
pages = {1399-1408},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 23. | Monteiro, O; Chen, C; Bingham, R; Argyrou, A; Buxton, R; Jonsson, C P; Jones, E; Bridges, A; Gatfield, K; Krauss, S; Lambert, J; Langston, R; Schweiger, S; Uings, I Pharmacological disruption of the MID1/a4 interaction reduces mutant Huntingtin levels in primary neuronal cultures Artikel Neurosci Lett, 2018, ISSN: 1872-7972 (Electronic)
0304-3940 (Linking). Links | BibTeX @article{RN13b,
title = {Pharmacological disruption of the MID1/a4 interaction reduces mutant Huntingtin levels in primary neuronal cultures},
author = {O Monteiro and C Chen and R Bingham and A Argyrou and R Buxton and C P Jonsson and E Jones and A Bridges and K Gatfield and S Krauss and J Lambert and R Langston and S Schweiger and I Uings},
url = {https://www.ncbi.nlm.nih.gov/pubmed/29499308},
doi = {10.1016/j.neulet.2018.02.061},
issn = {1872-7972 (Electronic)
0304-3940 (Linking)},
year = {2018},
date = {2018-01-01},
journal = {Neurosci Lett},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 22. | Unterbruner, K; Matthes, F; Schilling, J; Nalavade, R; Weber, S; Winter, J; Krauss, S MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression Artikel PLoS One, 13 (1), S. e0190437, 2018, ISSN: 1932-6203 (Electronic)
1932-6203 (Linking). Links | BibTeX @article{RN20b,
title = {MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression},
author = {K Unterbruner and F Matthes and J Schilling and R Nalavade and S Weber and J Winter and S Krauss},
url = {https://www.ncbi.nlm.nih.gov/pubmed/29293623},
doi = {10.1371/journal.pone.0190437},
issn = {1932-6203 (Electronic)
1932-6203 (Linking)},
year = {2018},
date = {2018-01-01},
journal = {PLoS One},
volume = {13},
number = {1},
pages = {e0190437},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2017
|
| 21. | Ercan, E; Eid, S; Weber, C; Kowalski, A; Bichmann, M; Behrendt, A; Matthes, F; Krauss, S; Reinhardt, P; Fulle, S; Ehrnhoefer, D E A validated antibody panel for the characterization of tau post-translational modifications Artikel Mol Neurodegener, 12 (1), S. 87, 2017, ISSN: 1750-1326 (Electronic)
1750-1326 (Linking). Links | BibTeX @article{RN27b,
title = {A validated antibody panel for the characterization of tau post-translational modifications},
author = {E Ercan and S Eid and C Weber and A Kowalski and M Bichmann and A Behrendt and F Matthes and S Krauss and P Reinhardt and S Fulle and D E Ehrnhoefer},
url = {https://www.ncbi.nlm.nih.gov/pubmed/29157277},
doi = {10.1186/s13024-017-0229-1},
issn = {1750-1326 (Electronic)
1750-1326 (Linking)},
year = {2017},
date = {2017-01-01},
journal = {Mol Neurodegener},
volume = {12},
number = {1},
pages = {87},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 20. | Griesche, N; Pesch, V; Nalavade, R; Weber, S; König, I; Schölling, M; Möhl, C; Krauß, S tFRAP: A FRAP-Based Technique to Monitor Protein Translation in Living Cells Artikel J Anal Bioanal Tech, 8 (6), 2017, ISSN: 2155-9872. Links | BibTeX @article{RN28b,
title = {tFRAP: A FRAP-Based Technique to Monitor Protein Translation in Living Cells},
author = {N Griesche and V Pesch and R Nalavade and S Weber and I König and M Schölling and C Möhl and S Krauß},
doi = {10.4172/2155-9872.1000390},
issn = {2155-9872},
year = {2017},
date = {2017-01-01},
journal = {J Anal Bioanal Tech},
volume = {8},
number = {6},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 19. | Schweiger, S; Matthes, F; Posey, K; Kickstein, E; Weber, S; Hettich, M M; Pfurtscheller, S; Ehninger, D; Schneider, R; Krauss, S Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex Artikel Sci Rep, 7 (1), S. 13753, 2017, ISSN: 2045-2322 (Electronic)
2045-2322 (Linking). Links | BibTeX @article{RN18b,
title = {Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex},
author = {S Schweiger and F Matthes and K Posey and E Kickstein and S Weber and M M Hettich and S Pfurtscheller and D Ehninger and R Schneider and S Krauss},
url = {https://www.ncbi.nlm.nih.gov/pubmed/29062069},
doi = {10.1038/s41598-017-12974-4},
issn = {2045-2322 (Electronic)
2045-2322 (Linking)},
year = {2017},
date = {2017-01-01},
journal = {Sci Rep},
volume = {7},
number = {1},
pages = {13753},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2016
|
| 18. | Griesche, N; Schilling, J; Weber, S; Rohm, M; Pesch, V; Matthes, F; Auburger, G; Krauss, S Regulation of mRNA translation by MID1: a common mechanism of expanded CAG repeat RNAs Artikel Front. Cell. Neurosci., 2016. Links | BibTeX @article{RN4l,
title = {Regulation of mRNA translation by MID1: a common mechanism of expanded CAG repeat RNAs},
author = {N Griesche and J Schilling and S Weber and M Rohm and V Pesch and F Matthes and G Auburger and S Krauss},
doi = {doi: 10.3389/fncel.2016.00226},
year = {2016},
date = {2016-01-01},
journal = {Front. Cell. Neurosci.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 17. | Schilling, J; Griesche, N; Krauß, S Mechanisms of RNA-Induced Toxicity in Diseases Characterised by CAG Repeat Expansions Artikel eLS. John Wiley & Sons, Ltd: Chichester., 2016. Links | BibTeX @article{RN32b,
title = {Mechanisms of RNA-Induced Toxicity in Diseases Characterised by CAG Repeat Expansions},
author = {J Schilling and N Griesche and S Krauß},
doi = {DOI: 10.1002/9780470015902.a0026464},
year = {2016},
date = {2016-01-01},
journal = {eLS. John Wiley & Sons, Ltd: Chichester.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 16. | Winter, J; Basilicata, M F; Stemmler, M P; Krauss, S The MID1 protein is a central player during development and in disease Artikel Front Biosci (Landmark Ed), 21 , S. 664-82, 2016, ISSN: 1093-4715 (Electronic)
1093-4715 (Linking). Links | BibTeX @article{RN22b,
title = {The MID1 protein is a central player during development and in disease},
author = {J Winter and M F Basilicata and M P Stemmler and S Krauss},
url = {http://www.ncbi.nlm.nih.gov/pubmed/26709798},
issn = {1093-4715 (Electronic)
1093-4715 (Linking)},
year = {2016},
date = {2016-01-01},
journal = {Front Biosci (Landmark Ed)},
volume = {21},
pages = {664-82},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2015
|
| 15. | Wagner, J; Krauss, S; Shi, S; Ryazanov, S; Steffen, J; Miklitz, C; Leonov, A; Kleinknecht, A; Goricke, B; Weishaupt, J H; Weckbecker, D; Reiner, A M; Zinth, W; Levin, J; Ehninger, D; Remy, S; Kretzschmar, H A; Griesinger, C; Giese, A; Fuhrmann, M Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies Artikel Acta Neuropathol, 130 (5), S. 619-31, 2015, ISSN: 1432-0533 (Electronic)
0001-6322 (Linking). Links | BibTeX @article{RN21b,
title = {Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies},
author = {J Wagner and S Krauss and S Shi and S Ryazanov and J Steffen and C Miklitz and A Leonov and A Kleinknecht and B Goricke and J H Weishaupt and D Weckbecker and A M Reiner and W Zinth and J Levin and D Ehninger and S Remy and H A Kretzschmar and C Griesinger and A Giese and M Fuhrmann},
url = {https://www.ncbi.nlm.nih.gov/pubmed/26439832},
doi = {10.1007/s00401-015-1483-3},
issn = {1432-0533 (Electronic)
0001-6322 (Linking)},
year = {2015},
date = {2015-01-01},
journal = {Acta Neuropathol},
volume = {130},
number = {5},
pages = {619-31},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2014
|
| 14. | Kohler, A; Demir, U; Kickstein, E; Krauss, S; Aigner, J; Aranda-Orgilles, B; Karagiannidis, A I; Achmuller, C; Bu, H; Wunderlich, A; Schweiger, M R; Schaefer, G; Schweiger, S; Klocker, H; Schneider, R A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling Artikel Mol Cancer, 13 (1), S. 146, 2014, ISSN: 1476-4598 (Electronic)
1476-4598 (Linking). Links | BibTeX @article{RN6b,
title = {A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling},
author = {A Kohler and U Demir and E Kickstein and S Krauss and J Aigner and B Aranda-Orgilles and A I Karagiannidis and C Achmuller and H Bu and A Wunderlich and M R Schweiger and G Schaefer and S Schweiger and H Klocker and R Schneider},
url = {http://www.ncbi.nlm.nih.gov/pubmed/24913494},
doi = {10.1186/1476-4598-13-146},
issn = {1476-4598 (Electronic)
1476-4598 (Linking)},
year = {2014},
date = {2014-01-01},
journal = {Mol Cancer},
volume = {13},
number = {1},
pages = {146},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 13. | Perez-Revuelta, B I; Hettich, M M; Ciociaro, A; Rotermund, C; Kahle, P J; Krauss, S; Monte, Di D A Metformin lowers Ser-129 phosphorylated alpha-synuclein levels via mTOR-dependent protein phosphatase 2A activation Artikel Cell Death Dis, 5 , S. e1209, 2014, ISSN: 2041-4889 (Electronic). Links | BibTeX @article{RN15b,
title = {Metformin lowers Ser-129 phosphorylated alpha-synuclein levels via mTOR-dependent protein phosphatase 2A activation},
author = {B I Perez-Revuelta and M M Hettich and A Ciociaro and C Rotermund and P J Kahle and S Krauss and D A Di Monte},
url = {http://www.ncbi.nlm.nih.gov/pubmed/24810045},
doi = {10.1038/cddis.2014.175},
issn = {2041-4889 (Electronic)},
year = {2014},
date = {2014-01-01},
journal = {Cell Death Dis},
volume = {5},
pages = {e1209},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 12. | Schweiger, S; Dorn, S; Fuchs, M; Kohler, A; Matthes, F; Muller, E C; Wanker, E; Schneider, R; Krauss, S The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu Artikel J Biol Chem, 289 (46), S. 31805-17, 2014, ISSN: 1083-351X (Electronic)
0021-9258 (Linking). Links | BibTeX @article{RN17b,
title = {The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu},
author = {S Schweiger and S Dorn and M Fuchs and A Kohler and F Matthes and E C Muller and E Wanker and R Schneider and S Krauss},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=25278022},
doi = {M113.541219 [pii]
10.1074/jbc.M113.541219},
issn = {1083-351X (Electronic)
0021-9258 (Linking)},
year = {2014},
date = {2014-01-01},
journal = {J Biol Chem},
volume = {289},
number = {46},
pages = {31805-17},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2013
|
| 11. | Krauss, S; Griesche, N; Jastrzebska, E; Chen, C; Rutschow, D; Achmuller, C; Dorn, S; Boesch, S M; Lalowski, M; Wanker, E; Schneider, R; Schweiger, S Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex Artikel Nat Commun, 4 , S. 1511, 2013, ISSN: 2041-1723 (Electronic)
2041-1723 (Linking). Links | BibTeX @article{RN8b,
title = {Translation of HTT mRNA with expanded CAG repeats is regulated by the MID1-PP2A protein complex},
author = {S Krauss and N Griesche and E Jastrzebska and C Chen and D Rutschow and C Achmuller and S Dorn and S M Boesch and M Lalowski and E Wanker and R Schneider and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/pubmed/23443539},
doi = {10.1038/ncomms2514},
issn = {2041-1723 (Electronic)
2041-1723 (Linking)},
year = {2013},
date = {2013-01-01},
journal = {Nat Commun},
volume = {4},
pages = {1511},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 10. | Krauss, S; Vorberg, I Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins Artikel Int J Cell Biol, 2013 , S. 704546, 2013, ISSN: 1687-8876 (Print)
1687-8876 (Linking). Links | BibTeX @article{RN31b,
title = {Prions Ex Vivo: What Cell Culture Models Tell Us about Infectious Proteins},
author = {S Krauss and I Vorberg},
url = {https://www.ncbi.nlm.nih.gov/pubmed/24282413},
doi = {10.1155/2013/704546},
issn = {1687-8876 (Print)
1687-8876 (Linking)},
year = {2013},
date = {2013-01-01},
journal = {Int J Cell Biol},
volume = {2013},
pages = {704546},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 9. | Nalavade, R; Griesche, N; Ryan, D P; Hildebrand, S; Krauss, S Mechanisms of RNA-induced toxicity in CAG repeat disorders Artikel Cell Death Dis, 4 , S. e752, 2013, ISSN: 2041-4889 (Electronic). Links | BibTeX @article{RN14b,
title = {Mechanisms of RNA-induced toxicity in CAG repeat disorders},
author = {R Nalavade and N Griesche and D P Ryan and S Hildebrand and S Krauss},
url = {http://www.ncbi.nlm.nih.gov/pubmed/23907466},
doi = {10.1038/cddis.2013.276},
issn = {2041-4889 (Electronic)},
year = {2013},
date = {2013-01-01},
journal = {Cell Death Dis},
volume = {4},
pages = {e752},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2011
|
| 8. | Araujo, J; Breuer, P; Dieringer, S; Krauss, S; Dorn, S; Zimmermann, K; Pfeifer, A; Klockgether, T; Wuellner, U; Evert, B O FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3 Artikel Hum Mol Genet, 20 (15), S. 2928-41, 2011, ISSN: 1460-2083 (Electronic)
0964-6906 (Linking). Links | BibTeX @article{RN1l,
title = {FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3},
author = {J Araujo and P Breuer and S Dieringer and S Krauss and S Dorn and K Zimmermann and A Pfeifer and T Klockgether and U Wuellner and B O Evert},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21536589},
doi = {ddr197 [pii]
10.1093/hmg/ddr197},
issn = {1460-2083 (Electronic)
0964-6906 (Linking)},
year = {2011},
date = {2011-01-01},
journal = {Hum Mol Genet},
volume = {20},
number = {15},
pages = {2928-41},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 7. | Liu, E; Knutzen, C A; Krauss, S; Schweiger, S; Chiang, G G Control of mTORC1 signaling by the Opitz syndrome protein MID1 Artikel Proc Natl Acad Sci U S A, 108 (21), S. 8680-5, 2011, ISSN: 1091-6490 (Electronic)
0027-8424 (Linking). Links | BibTeX @article{RN11b,
title = {Control of mTORC1 signaling by the Opitz syndrome protein MID1},
author = {E Liu and C A Knutzen and S Krauss and S Schweiger and G G Chiang},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=21555591},
doi = {1100131108 [pii]
10.1073/pnas.1100131108},
issn = {1091-6490 (Electronic)
0027-8424 (Linking)},
year = {2011},
date = {2011-01-01},
journal = {Proc Natl Acad Sci U S A},
volume = {108},
number = {21},
pages = {8680-5},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2010
|
| 6. | Kickstein, E; Krauss, S; Thornhill, P; Rutschow, D; Zeller, R; Sharkey, J; Williamson, R; Fuchs, M; Kohler, A; Glossmann, H; Schneider, R; Sutherland, C; Schweiger, S Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling Artikel Proc Natl Acad Sci U S A, 107 (50), S. 21830-5, 2010, ISSN: 1091-6490 (Electronic)
0027-8424 (Linking). Links | BibTeX @article{RN5e,
title = {Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling},
author = {E Kickstein and S Krauss and P Thornhill and D Rutschow and R Zeller and J Sharkey and R Williamson and M Fuchs and A Kohler and H Glossmann and R Schneider and C Sutherland and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/pubmed/21098287},
doi = {10.1073/pnas.0912793107},
issn = {1091-6490 (Electronic)
0027-8424 (Linking)},
year = {2010},
date = {2010-01-01},
journal = {Proc Natl Acad Sci U S A},
volume = {107},
number = {50},
pages = {21830-5},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2009
|
| 5. | Krauss, S; So, J; Hambrock, M; Kohler, A; Kunath, M; Scharff, C; Wessling, M; Grzeschik, K H; Schneider, R; Schweiger, S Point mutations in GLI3 lead to misregulation of its subcellular localization Artikel PLoS One, 4 (10), S. e7471, 2009. Links | BibTeX @article{RN10b,
title = {Point mutations in GLI3 lead to misregulation of its subcellular localization},
author = {S Krauss and J So and M Hambrock and A Kohler and M Kunath and C Scharff and M Wessling and K H Grzeschik and R Schneider and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19829694},
year = {2009},
date = {2009-01-01},
journal = {PLoS One},
volume = {4},
number = {10},
pages = {e7471},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2008
|
| 4. | al Yacoub, N; Romanowska, M; Krauss, S; Schweiger, S; Foerster, J PPARdelta is a type 1 IFN target gene and inhibits apoptosis in T cells Artikel J Invest Dermatol, 128 (8), S. 1940-9, 2008, ISSN: 1523-1747 (Electronic)
0022-202X (Linking). Links | BibTeX @article{RN24b,
title = {PPARdelta is a type 1 IFN target gene and inhibits apoptosis in T cells},
author = {N al Yacoub and M Romanowska and S Krauss and S Schweiger and J Foerster},
url = {https://www.ncbi.nlm.nih.gov/pubmed/18305567},
doi = {10.1038/jid.2008.32},
issn = {1523-1747 (Electronic)
0022-202X (Linking)},
year = {2008},
date = {2008-01-01},
journal = {J Invest Dermatol},
volume = {128},
number = {8},
pages = {1940-9},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
| 3. | Krauss, S; Foerster, J; Schneider, R; Schweiger, S Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3 Artikel Cancer Res, 68 (12), S. 4658-65, 2008. Links | BibTeX @article{RN7b,
title = {Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3},
author = {S Krauss and J Foerster and R Schneider and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18559511},
year = {2008},
date = {2008-01-01},
journal = {Cancer Res},
volume = {68},
number = {12},
pages = {4658-65},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2004
|
| 2. | Winter, J; Lehmann, T; Krauss, S; Trockenbacher, A; Kijas, Z; Foerster, J; Suckow, V; Yaspo, M L; Kulozik, A; Kalscheuer, V; Schneider, R; Schweiger, S Regulation of the MID1 protein function is fine-tuned by a complex pattern of alternative splicing Artikel Hum Genet, 114 (6), S. 541-52, 2004, ISSN: 0340-6717 (Print)
0340-6717 (Linking). Links | BibTeX @article{RN23b,
title = {Regulation of the MID1 protein function is fine-tuned by a complex pattern of alternative splicing},
author = {J Winter and T Lehmann and S Krauss and A Trockenbacher and Z Kijas and J Foerster and V Suckow and M L Yaspo and A Kulozik and V Kalscheuer and R Schneider and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15057556},
doi = {10.1007/s00439-004-1114-x},
issn = {0340-6717 (Print)
0340-6717 (Linking)},
year = {2004},
date = {2004-01-01},
journal = {Hum Genet},
volume = {114},
number = {6},
pages = {541-52},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
2001
|
| 1. | Trockenbacher, A; Suckow, V; Foerster, J; Winter, J; Krauss, S; Ropers, H H; Schneider, R; Schweiger, S MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation Artikel Nat Genet, 29 (3), S. 287-94, 2001. Links | BibTeX @article{RN19b,
title = {MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation},
author = {A Trockenbacher and V Suckow and J Foerster and J Winter and S Krauss and H H Ropers and R Schneider and S Schweiger},
url = {http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11685209},
year = {2001},
date = {2001-01-01},
journal = {Nat Genet},
volume = {29},
number = {3},
pages = {287-94},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
|
